রবিবার, ৫ মে, ২০১৩

This Is Earth As Seen By Smartphone Satellites

A few months ago, NASA sent some Nexus Ones into space to see if a smartphone could hold its own against the million dollar satellites already up there. The answer is "not exactly." When it comes to photography, it's probably best to stick with the space-professionals.

The trio of smartphone satellites coordinated to take hundreds of pictures of the blue marble, which were then sent back to Earth piecemeal over amateur radio waves for reassembly by space-enthusiast volunteers. That part was successful, though the pictures aren't exactly detailed. Between the transmission artifacting and the smartphone grade cameras it gets a little messy, but sort of awesomely so.

The phonesats burned up on reentry in late April so these composite shots are really all that remains from Android phones' first foray into satellite-hood. And while the photos are neat-lookin' in their own way, they definitely aren't "good." Maybe we should just try and perfect smartphone cameras here on Earth first. [NASA via Engadget]

Source: http://gizmodo.com/this-is-earth-as-seen-by-smartphone-satellites-490511420

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Air France-KLM losses mount in Q1

May 1 (Reuters) - Post position for Saturday's 139th Kentucky Derby at Churchill Downs after Wednesday's draw (listed as barrier, HORSE, jockey, trainer) 1. BLACK ONYX, Joe Bravo, Kelly Breen 2. OXBOW, Gary Stevens, D. Wayne Lukas 3. REVOLUTIONARY, Calvin Borel, Todd Pletcher 4. GOLDEN SOUL, Robby Albarado, Dallas Stewart 5. NORMANDY INVASION, Javier Castellano, Chad Brown 6. MYLUTE, Rosie Napravnik, Tom Amoss 7. GIANT FINISH, Jose Espinoza, Tony Dutrow 8. GOLDENCENTS, Kevin Krigger, Doug O'Neill 9. OVERANALYZE, Rafael Bejarano, Todd Pletcher 10. PALACE MALICE, Mike Smith, Todd Pletcher 11. ...

Source: http://news.yahoo.com/air-france-klm-losses-mount-q1-064329838.html

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Audience Development Startup LinkSmart Raises $5 Million From Foundry And Costanoa

LinkSmart logos_high-res_1157x276A little less than a year ago, a little company called LinkSmart launched to help publishers use text links to get their readers reading more. Now it has raised $5 million in Series B funding to take its technology for growing audiences and make it more widely available. The financing was led by Foundry Group and Costanoa Venture Partners.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/d1IrmUu-bqU/

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শুক্রবার, ৩ মে, ২০১৩

Seahorse's armor gives engineers insight into robotics designs

Thursday, May 2, 2013

The tail of a seahorse can be compressed to about half its size before permanent damage occurs, engineers at the University of California, San Diego, have found. The tail's exceptional flexibility is due to its structure, made up of bony, armored plates, which slide past each other. Researchers are hoping to use a similar structure to create a flexible robotic arm equipped with muscles made out of polymer, which could be used in medical devices, underwater exploration and unmanned bomb detection and detonation. Researchers, led by UC San Diego materials science professors Joanna McKittrick and Marc Meyers, detailed their findings in the March 2013 issue of the journal Acta Biomaterialia.

"The study of natural materials can lead to the creation of new and unique materials and structures inspired by nature that are stronger, tougher, lighter and more flexible," said McKittrick, a professor of materials science at the Jacobs School of Engineering at UC San Diego.

McKittrick and Meyers had sought bioinsipiration by examining the armor of many other animals, including armadillo, alligators and the scales of various fish. This time, they were specifically looking for an animal that was flexible enough to develop a design for a robotic arm.

"The tail is the seahorse's lifeline," because it allows the animal to anchor itself to corals or seaweed and hide from predators, said Michael Porter, a Ph.D. student in materials science at the Jacobs School of Engineering. "But no one has looked at the seahorse's tail and bones as a source of armor."

Most of the seahorse's predators, including sea turtles, crabs and birds, capture the animals by crushing them. Engineers wanted to see if the plates in the tail act as an armor. Researchers took segments from seahorses' tails and compressed them from different angles. They found that the tail could be compressed by nearly 50 percent of its original width before permanent damage occurred. That's because the connective tissue between the tail's bony plates and the tail muscles bore most of the load from the displacement. Even when the tail was compressed by as much as 60 percent, the seahorse's spinal column was protected from permanent damage.

McKittrick and Meyers' research group uses a unique technique that applies a series of chemicals to materials to strip them of either their protein components or their mineral components. That allows them to better study materials' structures and properties. After treating the bony plates in the seahorse's tail with the chemicals, they discovered that the percentage of minerals in the plates was relatively low?40 percent, compared to 65 percent in cow bone. The plates also contained 27 percent organic compounds?mostly proteins?and 33 percent water. The hardness of the plates varied. The ridges were hardest, likely for impact protection?about 40 percent harder than the plate's grooves, which are porous and absorb energy from impacts.

The seahorse's tail is typically made up of 36 square-like segments, each composed of four L-shaped corner plates that progressively decrease in size along the length of the tail. Plates are free to glide or pivot. Gliding joints allow the bony plates to glide past one another. Pivoting joints are similar to a ball-and-socket joint, with three degrees of rotational freedom. The plates are connected to the vertebrae by thick collagen layers of connective tissue. The joints between plates and vertebrae are extremely flexible with nearly six degrees of freedom (See picture).

"Everything in biology comes down to structures," Porter said.

The next step is to use 3D printing to create artificial bony plates, which would then be equipped with polymers that would act as muscles. The final goal is to build a robotic arm that would be a unique hybrid between hard and soft robotic devices. A flexible, yet robust robotic gripper could be used for medical devices, underwater exploration and unmanned bomb detection and detonation. The protected, flexible arm would be able to grasp a variety of objects of different shapes and sizes.

###

University of California - San Diego: http://www.ucsd.edu

Thanks to University of California - San Diego for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/128099/Seahorse_s_armor_gives_engineers_insight_into_robotics_designs

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Engineer who warned over Bangladesh building held, toll tops 500

By Ruma Paul

DHAKA (Reuters) - Police investigating the collapse of a Bangladesh factory building that killed more than 500 people have arrested an engineer who warned the day before that the eight-storey complex was unsafe.

The arrest of engineer Adbur Razzak brought to nine the number of people held over the April 24 disaster, which has put the spotlight on the many Western clothing retailers who use Bangladesh as a source of cheap goods.

One firm whose garments were being made in the doomed building, Canada's Loblaw, said on Thursday it would continue to produce clothes in Bangladesh but promised to improve the facilities it uses there.

The death toll from Bangladesh's worst industrial accident rose to 501 on Friday, with the scores of relatives still gathered at the site in a Dhaka suburb clutching photographs of loved ones attesting to the many more still missing.

Engineer Razzak had been called to Rana Plaza in Savar, 20 miles north of the capital, by its owner when cracks appeared in concrete pillars the day before the accident.

Despite his warning that the building was unsafe -- quoted in local media hours before it came crashing to the ground -- thousands of mostly female workers were sent back into its upper storey factories when the morning shift began the next day.

Police said Razzak had been arrested because he had been involved in the original construction of the building.

LOW WAGES

Duty-free access offered by Western countries and low wages have helped turn Bangladesh's garment exports into a $19 billion a year industry, with 60 percent of clothes going to Europe.

The European Union has said it is considering trade action against Bangladesh, which has preferential access to EU markets for its garments, to pressure Dhaka to improve safety standards.

About 3.6 million people work in Bangladesh's garment industry, making it the world's second-largest apparel exporter after China. Some earn as little as $38 a month, conditions Pope Francis on Wednesday likened to "slave labor".

Walt Disney Co said in March it would no longer allow its branded products to be made in five countries, including Bangladesh, in an effort to ensure production in safe conditions.

Loblaw Cos Ltd, which was using a factory at Rana Plaza to make clothes for its discount "Joe Fresh" line, said it would remain in Bangladesh because well-run factories can help lift people out of poverty in developing countries.

Loblaw promised to start a relief fund for victims and said it would add "building integrity" to its audit of suppliers' facilities.

"I am deeply troubled. I am troubled that despite a clear commitment to the highest standards of ethical sourcing, our company can still be part of such an unspeakable tragedy," Executive Chairman Galen Weston told reporters.

Other retailers that were using factories at Rana Plaza, or had done so in the past year, include Britain's Primark -- which has also pledged to compensate victims -- Matalan, Spain's Mango and Benetton.

There were about 3,000 people inside the complex, which was built on swampy land, when it collapsed. About 2,500 people have been rescued, many injured, but many remain unaccounted for.

The building's owner, Mohammed Sohel Rana, his father, four factory owners and two engineers have since been arrested, while the local mayor has been suspended from office accused of improperly approving its construction.

It was the third deadly incident in six months to raise questions about worker safety and labor conditions in Bangladesh.

In November, scores died in a garment-factory fire in Dhaka, many of them because supervisors ordered workers back to their stations even as an alarm rang and smoke rose through an internal staircase.

Human-rights groups say there has never been a case in which a factory owner was prosecuted over the deaths of workers.

(Additional reporting by Serajul Quadir; Writing by Alex Richardson; Editing by Paul Tait)

Source: http://news.yahoo.com/engineer-warned-over-bangladesh-building-held-toll-tops-065242287.html

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Extend search for life beyond 'alien Earths,' astronomer urges

NASA / Ames / JPL-Caltech

This artist's concept depicts Kepler-62e, a super-Earth planet in the habitable zone of a star smaller and cooler than the sun, located about 1,200 light-years from Earth in the constellation Lyra.

By Mike Wall
Space.com

Scientists searching for signs of life beyond our solar system should keep an open mind, for planets very different than Earth may well be habitable, a prominent researcher says.

While it may seem natural to zero in on "alien Earths," such a narrow focus would exclude many potentially life-supporting exoplanets, whose diversity continues to astound astronomers, says Sara Seager of MIT.

And researchers can't afford to be so picky, she adds, since they'll be able to get in-depth looks at just a handful of alien worlds for the foreseeable future. [9 Exoplanets That Could Host Alien Life]

"The number of planets that we're going to be able to see in our lifetime ? and look at their atmospheres for signs of life?? is so small that we're forced to be open-minded," Seager told Space.com.

Seager discusses exoplanet?habitability in a review article published online Thursday?in the journal Science.

A dazzling diversity of alien worlds
Scientists discovered the first alien planet around a sunlike star in 1995. Since then, the tally has grown to more than 700 (or more than 800, depending on whose list is consulted), with thousands more candidates waiting to be confirmed by follow-up observations.

Some of these alien worlds are broadly similar to planets in our own solar system. But many others are truly alien ? enormous "hot Jupiters" that whip around their parent stars at extremely close range, for example, or "rogue planets" that cruise through the cold depths of space alone, with no parent star.

"If there is one important lesson from exoplanets, it is that anything is possible within the laws of physics and chemistry," Seager writes in the Science article. "Planets of almost all masses, sizes and orbits have been detected, illustrating not only the stochastic nature of planet formation but also a subsequent migration through the planetary disk from the planet?s place of origin." [The Strangest Alien Planets]

Intriguingly, a number of planets have been spotted orbiting within the so-called "habitable zone" ? that just-right range of distances from a star where liquid water is possible on a world's surface. (Water is required for life as we know it here on Earth and has thus spurred astrobiologists to "follow the water" on other planets, Seager writes.)

Just where this habitable zone lies for each planet depends on a number of factors, most crucially its host star's brightness and the planet's atmospheric makeup.

"It's really all about the greenhouse gases," Seager told Space.com. "The greenhouse gases are like a blanket that moderates the temperature at the surface."

Extending the habitable zone
The conventional definition of the habitable zone assumes a roughly Earth-like atmosphere, dominated by nitrogen, carbon dioxide and water vapor. But the huge diversity of alien worlds argues for a new way of thinking, writes Seager, who literally wrote the book on exoplanet atmospheres ("Exoplanet Atmospheres: Physical Processes," Princeton University Press, 2010).

For example, large and/or chilly alien worlds could conceivably hang onto their gaseous molecular hydrogen, which long ago escaped from small planets such as Earth, Venus and Mars.

Hydrogen is a powerful greenhouse gas that could make liquid water possible on a number of worlds far beyond the outer edge of the traditional habitable zone ? and perhaps even on seemingly frigid rogue planets, Seager writes.

Similarly, the habitable zone may extend inward, toward the host star, on "dry" rocky planets whose atmospheres have much less water vapor than Earth's does. So it's best to consider alien planets' potential to support life individually, on a case-by-case basis, Seager says.

Looking for life
Seager and others stress that a better understanding of exoplanet habitability is key to the next phase of the alien life hunt, which seeks to search promising candidates' atmospheres for water vapor and gases that may have been produced by life.

Astronomers have already scanned the air of a few dozen planets using NASA's Hubble Space Telescope and other instruments, Seager said. But those were hot Jupiters with big, puffy atmospheres ? relatively easy targets that aren't intriguing from an astrobiological perspective.

Scientists plan to do the same with smaller, potentially habitable worlds soon, Seager said. They'll use the Transiting Exoplanet Survey Satellite, which NASA recently approved for a 2017 launch, to identify promising candidates relatively close to Earth. Then NASA's James Webb Space Telescope?(which is scheduled to blast off in 2018) will follow up, getting an in-depth look at these worlds' air.

Though JWST is designed to be incredibly powerful, the $8.8 billion instrument will probably only be able to investigate the atmospheres of exoplanets that lie within a few tens of light-years from Earth, Seager added.

Seager said she hopes her review article in Science helps her fellow astronomers make the most of this small pool of observable candidates.

"I hope it gets people to realize that so many types of worlds could be habitable, and that our chance of finding one is higher when we accept that," she told Space.com.

Follow Mike Wall on Twitter?@michaeldwall?and?Google+.?Follow us @Spacedotcom, Facebook?or Google+. Originally published on?Space.com.

Copyright 2013 Space.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://feeds.nbcnews.com/c/35002/f/653377/s/2b7245c0/l/0Lscience0Bnbcnews0N0C0Inews0C20A130C0A50C0A20C180A233340Eextend0Esearch0Efor0Elife0Ebeyond0Ealien0Eearths0Eastronomer0Eurges0Dlite/story01.htm

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America's Internship! (talking-points-memo)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/303159047?client_source=feed&format=rss

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Breeze Through Grade School With Multiplication Cheat Sheet Socks

They say cheaters never prosper, but those people obviously never managed to score an A+ by looking at someone else's exam. So if you're having a bit of a rough time mastering your multiplication tables, just grab a pair of these Cheat Feet socks and don't sweat your next test.

All you need is $14 and a plausible excuse for taking your shoes off at school. We recommend either claims of some kind of athlete's foot, or tugging at your teacher's heart strings by pointing out your shoes have gotten uncomfortably small and your parents can't afford to buy you a new pair. They'll be too teary eyed to notice you constantly glancing at your feet. [Woodpecker Laboratories via Holycool]

Source: http://gizmodo.com/breeze-through-grade-school-with-multiplication-cheat-s-488992378

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Close offshore tax loopholes, says finance committee | iPolitics

The Canada Revenue Agency should apply the sometimes controversial General Tax Avoidance Rule in a bid to curb the use of offshore tax havens to avoid Canadian taxes, Parliament?s finance committee recommended Wednesday.

In a report tabled in the House of Commons following weeks of hearings into the use of offshore tax havens that stretched over two parliaments, the committee called on the government to continue to shut down loopholes being used to avoid taxes. It also wants the federal government to give the CRA more powers to obtain business identification information ? including the power to withhold certain refunds until the information is provided.

The committee, headed by Conservative MP James Rajotte, also urged the federal government to force companies like banks, that [...]

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Source: http://www.ipolitics.ca/2013/05/01/close-offshore-tax-loopholes-says-finance-committee/

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Adobe Lightroom product manager demonstrates RAW processing on iPad

Adobe Lightroom product manager demonstrates RAW processing on iPad

If editing DSLR photos on an iPad in their original, RAW format is the holy grail for many professional photographers and hobbyist alike, editing DSLR photos on an iPad, in RAW, using Adobe's workflow is likely the holiest of holies. It just might also be a reality, if not today, then at some point in a future that's near-ish. In fact, it's already been previewed on popular photography podcast, The Grid. Here's the description:

Tom Hogarty, Adobe's group product manager for Lightroom, brings a sneak peek to the future of processing raw photos on a tablet. Although Tom wouldn't reveal a launch date for the new prototype he did demonstrate some of the features on an iPad, and also offered several details about its features.

My RAW workflow today consists of yanking the SD card from my camera, slapping it into my rMPB, loading images into Lightroom (or more often, Aperture), right-clicking, and choosing Edit in Photoshop. When it comes to photography, I'm still a truck driver. Of course, that workflow comes with a camera bag that often feels as heavy as a truck.

The idea of being on the road, with only a DSLR strapped across my shoulder and an iPad mini in my jacket pocket, and being able to pull in photos, in DNG Smart Preview, and triage and pre-process them... That idea holds a lot of appeal. And it feels like the future.

No word yet on when, where, and how Lightroom for iPad will appear, or how well a full on RAW workflow will really perform, but I want it now. If you shoot RAW, let me know what you think -- is Lightroom for iPad in your future?

Source: The Grid via The Verge

(Demo starts 18 min. in.)

    


Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/YaeiJJrARBU/story01.htm

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GLOCK Donates $115,000 & Pistols to 4 Organizations at 2013 NRA ...

Team GLOCK and Gunny to make guest appearances at GLOCK booth in Houston, TX??

Glock Pistols

Glock Pistols

SMYRNA, Ga. (May 2, 2013)?? Today?GLOCK, Inc.?announced its participation in the?142nd?NRA Annual Meetings and Exhibits, held at the George R. Brown Convention Center in Houston, TX, May 3-5, 2013. GLOCK will donate $115,000 to four industry organizations at the Annual Meeting, as well as exhibit its products in Booth #2129. Guest appearances will be made by?Team GLOCK?members?KC Eusebio,?Tori Nonaka?and?Michelle Viscusi, along with GLOCK?s celebrity spokesperson?R. Lee Ermey (?Gunny?).

GLOCK will present generous donations to four key organizations (outlined below);?the ceremony for all four donations with organization representatives will take place at the GLOCK booth (#2129) on May 3, 2013 at 8:20 a.m.

1.???????$50,000 to the?National Rifle Association (NRA)

2013 is the fourth consecutive year that GLOCK will make a $50,000 donation to the NRA, America?s foremost defender of Second Amendment rights; the organization advocates for the promotion of firearm ownership, as well as marksmanship, firearm safety and the protection of hunting and self-defense in the United States.

2.???????$50,000 to the?NRA Wittington Center

This $50,000 donation marks the fifth consecutive year that GLOCK has donated to the NRA Whittington Center, the most comprehensive shooting facility in America today, complete with 15 shooting ranges, classrooms and a dining facility. It hosts recreational shooting and guided hunts as well as camping, hiking, mountain biking and horseback riding activities.

3.???????$15,000 to the?NRA Wittington Center Adventure Camp

GLOCK will make a $15,000 donation, for the eleventh consecutive year, to the NRA Whittington Center Adventure Camp, a unique place where young men and women have the opportunity to learn the fundamentals of pistol, rifle and shotgun shooting in a positive environment.

4.???????30 pistols to the?NRA Law Enforcement Division (LED)?

GLOCK will donate 30 pistols to the LED for the sixth consecutive year. This event held in Albuquerque, NM, is the NRA?s premiere annual shooting competition where Law Enforcement officers from around the globe compete to test their shooting skills.

?The NRA and its related organizations continue to uphold the values of firearm education and safety,? shared Josh Dorsey, GLOCK Vice President. ?We at GLOCK, Inc. are delighted to contribute to the ongoing efforts of the NRA to defend our Second Amendment right and to support the firearm industry.?

The 142nd?NRA Annual Meetings and Exhibits will be held at the George R. Brown Convention Center in the heart of downtown Houston, TX, May 3-5, 2013, with more than 550 exhibitors covering more than 400,000 square feet of exhibit hall space, with educational seminars, celebrities and special events.

?

About GLOCK, Inc.
The GLOCK GROUP is a leading global manufacturer of pistols and accessories. GLOCK?s superior engineering has produced a pistol with only 34 parts and a rugged polymer-frame, providing industry-leading reliability shot after shot. GLOCK is renowned for its pistols which are safe, featuring three safeties; simple, offering a low number of components to provide reliability; and fast, with no encumbering parts to slow the speed to fire. This combination makes GLOCK pistols the first choice among consumers and law enforcement, with approximately 65 percent of agencies within the United States choosing to carry GLOCK. Austrian-engineered, the group has manufacturing facilities in the United States and Austria. Based in Smyrna, Ga., GLOCK, Inc. is an advocate for our nation?s law enforcement and military personnel, as well as all citizens? Second Amendment right to bear arms. For more information, please visit?http://us.glock.com.

Source: http://www.ammoland.com/2013/05/glock-dosnates-115000-pistols-to-4-organizations-nra-annual-meeting/

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NJ gov signs overdose law, Bon Jovi applauds it

PATERSON, N.J. (AP) ? Just a few months after his daughter survived a drug overdose, Jon Bon Jovi joined New Jersey Gov. Chris Christie Thursday for the signing of a law to encourage reporting of overdoses so victims don't end up dead.

Bon Jovi called the law a lifesaver and encouraged other states to do the same.

"I hope that Governor Christie's actions here will cause other states to stand up and to pay attention and also to follow in his footsteps," Bon Jovi said before accompanying the Republican governor on a visit with patients at a drug rehabilitation center.

The New Jersey law seeks to assure timely medical treatment for overdose victims by encouraging people to seek help without fear of being arrested for drug possession.

Bon Jovi's daughter overdosed in a dorm at Hamilton College in upstate New York last year. Prosecutors dropped drug charges against Stephanie Bongiovi and another student under that state's good Samaritan overdose-reporting law.

Bon Jovi, who has a home in New Jersey, did not bring up his daughter's case at the bill-signing, and neither did the governor. In a December interview, Bon Jovi said he was shocked to learn of her overdose.

"She was doing great. Then a sudden and steep decline. Hopefully, we caught it when we did and that's the end of it. But who knew?" said Bon Jovi, a father of four.

The governor and singer told patients during their visit they should be proud of their recovery.

Christie has called the war on drugs a failure and has pushed for mandatory treatment for all non-violent drug offenders.

As elected officials, the governor said Thursday, "it's our obligation to ensure that we are doing everything we can to prevent tragic deaths from drug overdoses."

Families who have loved ones who died of drug overdoses also attended the event, many holding up pictures of those they lost. If people aren't afraid to call 911 in overdose cases, they said, more lives will be saved.

Taking a two-pronged approach to preventing drug overdose deaths, the New Jersey law also provides civil, criminal and professional immunity to health care professionals who prescribe or administer any FDA-approved treatment for drug overdoses. Lay people who administer antidotes in an emergency will also be protected.

Legislative sponsors of the bill say New Jersey is now the 12th state to provide good Samaritan protections for those who report overdoses, and the 11th to give legal immunity to those who administer antidotes.

The law extends protection even to those on parole and probation from being arrested, charged or prosecuted for small amounts of drugs when reporting an overdose.

The measure includes the core of two bills that the governor, a former federal prosecutor, had previously vetoed. He insisted that the law spell out that no immunity will exist for drug traffickers. Protections were also removed for people with restraining orders against them and those facing forfeiture of assets.

"This is a real triumph of public health policy and we thank Gov. Christie and the Legislature for working so hard to come to an agreement," said Roseanne Scotti, state director of the New Jersey Drug Policy Alliance, an advocacy group for drug policy reforms.

Source: http://news.yahoo.com/nj-gov-signs-overdose-law-bon-jovi-applauds-194121889.html

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Heart cells change stem cell behavior

May 2, 2013 ? Stem cells drawn from amniotic fluid show promise for tissue engineering, but it's important to know what they can and cannot do. A new study by researchers at Rice University and Texas Children's Hospital has shown that these stem cells can communicate with mature heart cells and form electrical couplings with each other similar to those found in heart tissue. But these electrical connections alone do not prompt amniotic cells to become cardiac cells.

The study led by bioengineer Jeff Jacot, who has a joint appointment at Rice and Texas Children's, is part of ongoing research into repairing the hearts of infants born with congenital defects. Jacot's lab is designing scaffold patches that can be implanted into infant hearts. The patches, seeded with stem cells from the mother's own amniotic fluid, would ideally prompt the growth of healthy tissue that would not be rejected.

But to get there, researchers have to figure out how signals that are passed from cell to cell might guide stem cells to differentiate into heart tissue.

In a paper that appears today in the Journal of Cellular and Molecular Medicine, Jacot and his team found that amniotic fluid stem cells that are cultured with but physically separated from rat heart cells (to keep them from fusing) don't differentiate into heart cells. But the stem and heart cells do communicate through channels in the thin membrane that allow ions and small molecules to pass.

"People have suggested that if amniotic fluid cells are in an environment where they're near heart cells, something happens that causes differentiation of the amniotic fluid cells into cardiac tissue," Jacot said. "We found that isn't the case."

He said researchers have seen other types of stem cells take on the characteristics of cardiac cells and determined it was because the cells had fused together. "You get a single cell with proteins from both the stem cells and the heart cells," he said.

Jacot wanted to see if amniotic cells could take on the characteristics of heart cells if they weren't allowed to fuse. "We showed there's no evidence of actual cardiac differentiation, although there were some changes in protein expression (among the stem cells)," he said. But the stem cells "become electrically coupled to each other, like cardiac cells do with each other. That was the main finding: We do get very good electrical coupling, which we call functional gap junction connections.

"Electrical ions or really small molecules that are in one cell can diffuse directly into a cell next to it," he said. "It's like they put holes in their membranes when they're up against each other."

Knowing what signals are passed is of great value as researchers figure out how to prompt stem cells to differentiate into the desired tissue, Jacot said.

He said other labs are studying how injecting amniotic fluid stem cells directly into hearts can help recovery after a heart attack. "There are a lot of people doing this with bone marrow-derived stem cells in the U.S., including two of the biggest groups in Houston, the Methodist Hospital and the Texas Heart Institute," Jacot said. "They seem to find what we call paracrine signaling effects, where the stem cells draw in more blood vessel-forming cells. There's some discussion as to whether they stabilize the cells, but don't seem to actually make new heart tissue."

Jacot said there are probably many ways to get amniotic fluid stem cells to differentiate into viable tissue for medical uses, and the new results are just a small step toward the goal of finding the best way.

"What we've observed is a little removed from any kind of translational therapeutic aspect," he said. "But we feel what we've observed will help us understand amniotic fluid stem cells in this environment."

Co-authors are Rice graduate student Jennifer Petsche Connell, Rice junior Emily Augustini and maternal-fetal specialists Kenneth Moise Jr. and Anthony Johnson. Jacot is an assistant professor of bioengineering at Rice, director of the Pediatric Cardiac Bioengineering Laboratory at the Congenital Heart Surgery Service at Texas Children's and an adjunct assistant professor at Baylor College of Medicine.

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The above story is reprinted from materials provided by Rice University.

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Journal Reference:

  1. Jennifer Petsche Connell, Emily Augustini, Kenneth J. Moise, Anthony Johnson, Jeffrey G. Jacot. Formation of functional gap junctions in amniotic fluid-derived stem cells induced by transmembrane co-culture with neonatal rat cardiomyocytes. Journal of Cellular and Molecular Medicine, 2013; DOI: 10.1111/jcmm.12056

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/6cJLvFYjgWY/130502142700.htm

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Obama to pitch immigration overhaul in Mexico

FILE - In this April 30, 2013 file photo, President Barack Obama answers questions during his new conference in the Brady Press Briefing Room of the White House in Washington. The president aims to assure Latin America that the U.S. is serious about immigration reform when he travels to Mexico and Costa Rica, beginning Thursday. (AP Photo/Evan Vucci, File)

FILE - In this April 30, 2013 file photo, President Barack Obama answers questions during his new conference in the Brady Press Briefing Room of the White House in Washington. The president aims to assure Latin America that the U.S. is serious about immigration reform when he travels to Mexico and Costa Rica, beginning Thursday. (AP Photo/Evan Vucci, File)

(AP) ? President Barack Obama is headed to Mexico with a domestic ambition at the top of his travel agenda. To sell his immigration overhaul back home, he needs a growing economy in Mexico and a Mexican president willing to help him secure the border.

Obama was to fly to Mexico City on Thursday to meet with President Enrique Pena Nieto, eager to promote Mexico's economic success and the neighboring country's place as the second largest export market for U.S. goods and services. Mexicans will be hanging on the president's words, but Obama also has in mind an important audience back in the United States.

Though the role played by Latino voters in last year's U.S. presidential election gets much credit for the current momentum for changing immigration laws and providing a path to citizenship for 11 million immigrants in the U.S. illegally, another reason for the change in attitudes is that stronger border protections and the recession have been disincentives to cross into the U.S. As a result, illegal immigration has declined.

"With Mexico, first and foremost, they are critical to our ability to secure the border," said Ben Rhodes, an Obama deputy national security adviser. "All the immigration plans that have been contemplated put a focus on securing the border as an essential priority and starting point for immigration reform."

Even better than a strong border is an economy that keeps people from fleeing.

"If the Mexican economy is growing, it forestalls the need for people to migrate to the United States to find work," Rhodes added.

Eager to focus on the economy and immigration, the administration is downplaying Pena Nieto's recent steps to end the broad access Mexico gave U.S. security agencies to help fight drug trafficking and organized crime under his predecessor, Felipe Calderon. Still, the changes are likely to be a subject during the two leaders' private talks. Obama said this week he wouldn't judge the new moves until he heard directly from Mexican officials.

Pena Nieto took office in December, and for Obama the trip is an opportunity to take his measure of the Mexican leader early in his tenure.

"It's really important to go there while this new president is forming his own plans and judgments about what he's going to do about the border, about where he's going to be on immigration, about where he is on trade," U.S. Chamber of Commerce President/CEO Thomas Donohue said in an interview.

The chamber long has worked to improve U.S.-Mexico trade, noting that now about 6 million U.S. jobs depend on commerce with Mexico.

Striking the right note on border security is key, Donohue said, because it is a central to winning support in Congress for the rest of the immigration legislation.

"That's what everybody wants to hear, and we have to do that in a way that makes these guys down there feel like we're doing it in conjunction with them and for them, so we can do this thing on immigration well, so we can expand our trade, so we can deal with our political issues as they are trying to deal with theirs," Donohue said.

Still, with 33 million U.S. residents of Mexican origin, Obama's message in Mexico is also bound to resonate in the U.S., where Latinos could increase pressure on Congress to act.

"It helps keep these passions alive as far as an issue to promote for the administration," said Carl Meacham, a former senior Latin America adviser on the Senate Foreign Relations Committee.

But Meacham, now director of the Americas program at the Center for Strategic and International Studies, cautioned that despite some bipartisan support to create a path to citizenship in the immigration bill, there is skepticism in Latin America. "They've been brought to the altar so many times by different American administrations that there's a little bit of a lack of trust," he said.

For Pena Nieto, Obama's visit is a chance for him to showcase his country's economic gains. After suffering along with the U.S. during the recession, its economy is now growing at a better clip than that of the U.S. Per capita income has gone from an annual $7,900 two years ago to $10,146. But Diana Negroponte, a Latin America expert at the Brookings Institution, says corruption remains endemic, human rights are still a problem, and efforts to change and improve the judicial system have been too slow.

"There is concern on our side of the border that greater help needs to be given in order for Mexico to reform its system," she said.

Pena Nieto's changes in the security relationship with the U.S. have prompted some U.S. officials to speculate that the new president might be embracing the policies of his Institutional Revolutionary Party, which long has favored centralized political and bureaucratic control.

Among those watching the new steps is Sen. Patrick Leahy, D-Vt., who has held up $228 million sought by the Obama administration for Mexico under a security cooperation agreement. Under the agreement, known as the Merida Initiative, Congress has already given Mexico more than $1.9 billion in aid since 2008.

But Leahy, chairman of the Senate Appropriations subcommittee that oversees the State Department budget, has been a critic of how the money has been used and with the results.

"Congress has been asked for a significant new investment, but it's not clear what the new Mexican government's intensions are," Leahy said in a statement to The Associated Press. "We're in a period of uncertainty until we know enough to be able to reset that part of our relationship. I'm not ready to sign off on more money without a lot more details."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-05-02-US-Obama/id-ef50c2e686414c47a178eaa532f81406

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Stem cell discovery could aid research into new treatments

May 2, 2013 ? Scientists have made a fundamental discovery about how the properties of embryonic stem cells are controlled.

The study, which focuses on the process by which these cells renew and increase in number, could help research to find new treatments.

Researchers have found that a protein, which switches on genes to allow embryonic stem cells to self-renew, works better when the natural occurring level of the protein is reduced.

It was previously thought that once levels of this protein -- called Oct 4 -- were reduced the numbers of new stem cells being produced would also fall.

The finding will inform stem cell research, which is looking to find treatments for conditions including Parkinson's, motor neuron, liver and heart disease.

During embryonic development, cells that have the capacity to become any cell type in the body -- called pluripotent stem cells -- can either renew themselves by multiplying in number or differentiate to become cells found in different parts of the body, for instance skin or liver.

This need for pluripotent cells to increase in number is important so that there is a sufficient supply of them to be differentiated into other cell types.

Scientists at the Medical Research Council Centre for Regenerative Medicine at the University of Edinburgh found that when there were lower levels of Oct 4, the protein bound much more tightly to key parts of DNA in cells.

The strong attraction of Oct 4 to these sections of DNA enabled the efficient switching on of key genes that caused pluripotent stem cells to renew.

The findings could help to improve the way in which stem cells are cultured in the laboratory, providing a better understanding of the processes needed for cells to divide and multiply or to generate different cell types.

The study, published in the journal Cell Stem Cell, was funded by the Medical Research Council, the Wellcome Trust, the Biotechnology and Biological Sciences Research Council and the Human Frontier Science Programme

Professor Ian Chambers, of the MRC Centre for Regenerative Medicine at the University, who led the study, said: "What we found was a complete surprise, as we thought that when levels of this key protein were reduced the numbers of pluripotent stem cells being generated would also fall. Instead, it appears that when the levels of Oct 4 are lower, the balance is tipped in favour of self-renewal over stem cell differentiation."

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The above story is reprinted from materials provided by University of Edinburgh.

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Journal Reference:

  1. Violetta Karwacki-Neisius, Jonathan G?ke, Rodrigo Osorno, Florian Halbritter, Jia?Hui Ng, Andrea?Y. Wei?e, Frederick?C.K. Wong, Alessia Gagliardi, Nicholas?P. Mullin, Nicola Festuccia, Douglas Colby, Simon?R. Tomlinson, Huck-Hui Ng, Ian Chambers. Reduced Oct4 Expression Directs a Robust Pluripotent State with Distinct Signaling Activity and Increased Enhancer Occupancy by Oct4 and Nanog. Cell Stem Cell, 2013; 12 (5): 531 DOI: 10.1016/j.stem.2013.04.023

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/7HWyL-X6AIc/130502131903.htm

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বৃহস্পতিবার, ২ মে, ২০১৩

New robots crawl like sea turtles

Researchers have designed a new type of robot modeled on sea turtles known as FlipperBot. This is the first robot to use flippers against pliable surfaces and has moved the work toward amphibious robots forward.

By Charles Q. Choi,?TechNewsDaily / April 24, 2013

Georgia Tech associate professor Daniel Goldman and researcher Nicole Mazouchova watch FlipperBot move through a bed filled with poppy seeds.

Georgia Tech/ Gary Meek

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Flippered robots inspired by sea-turtle hatchlings could shed light on how the ancestors of terrestrial animals first evolved to crawl on land, researchers say.

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Such research could also lead to amphibious robots that can tackle both land and sea, investigators added.

Scientists are designing robots that can go where humans cannot or should not go, and often rely on inspiration from nature to do so. For instance,?snakelike robots?could, in principle, slither into crevices to help find disaster victims.

Challenging environments for robots to cross include?sand, gravel, soil, mud and other unstable granular surfaces?that can deform around legs in complex ways. To learn new ways to navigate such ground, Daniel Goldman, a physicist at the Georgia Institute of Technology in Atlanta, and his colleagues investigated sea-turtle hatchlings.

"These little turtles are remarkably effective at moving over solid ground, with limbs designed for moving in fluid," Goldman told TechNewsDaily.

The researchers analyzed 25 baby loggerhead sea turtles from nests on Jekyll Island, one of Georgia's coastal islands, at night. They investigated how the turtles crawled on tracks of beach sand housed in a truck parked near the beach, video-recording them as they moved in the darkness toward a light that simulated the moon. [See also:?10 Animal-Inspired Robots]

Goldman and his colleagues Nicole Mazouchova and Paul Umbanhowar were surprised to learn the hatchlings moved about as quickly on soft sand as they did on hard sand.

"The turtles insert their flippers just deep enough into soft sand so that the material does not yield behind the flipper as they move," Goldman said. "That means the sand doesn't flow around the flippers, and they don't slip ? so they can propel themselves."

The key to performing well, regardless of the conditions of the sand, seemed to lie in how the turtles controlled their wrists.

"On hard ground, their wrists locked in place, and they pivoted about a fixed arm," Goldman said. "On soft sand, they put their flippers into the sand, and the wrist would bend as they moved forward. We decided to investigate this using a robot model."

These findings led to the development of FlipperBot, the first robot to employ flippers against malleable surfaces. The small droid is about 7.5 inches (19 centimeters) long, weighs 2 lbs. (970 grams), and has two motor-driven flippers with flexible wrists similar to sea turtle wrists

Source: http://rss.csmonitor.com/~r/feeds/science/~3/4vJsgtTY6gE/New-robots-crawl-like-sea-turtles

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Digital fees pay off for 2 top-selling newspapers

NEW YORK (AP) ? The Wall Street Journal remains the top-selling U.S. daily newspaper, but The New York Times has surpassed USA Today for second, thanks to an expansion into digital subscriptions, according to a report released Tuesday by an industry group.

The Journal's weekday circulation averaged 2.38 million from October through March, the period covered by the report from the Alliance for Audited Media. That was a 12 percent increase from the same period a year ago, the AAM said. Most of the growth came in digital subscriptions, which accounted for nearly 900,000, or 40 percent, of the total circulation at the newspaper, which is owned by News Corp.

The New York Times began charging for unlimited access to its heavily trafficked website two years ago. The move has helped boost its paid circulation by reeling in more subscribers who are willing to pay for unlimited digital access the newspaper's content. The Times' weekday circulation averaged 1.87 million during the latest period, an 18 percent increase from last year. The figure included digital circulation of 1.13 million, a 32 percent increase from last year.

AAM's rules allow publications to count as multiple subscriptions the same person's paid usage on multiple outlets, such as a paper newspaper, a website and a tablet computer.

AAM's methods for tracking circulation have changed in the past few years as newspaper publishers attempt to counter a decline in paid readership of their print editions and an even sharper drop in the advertising sales that bring in most of the industry's revenue. One of the biggest changes has occurred on the Web and on mobile devices, where newspapers are increasingly requiring readers to pay a fee to gain unlimited access to digital content that was once free. The AAM includes paid digital subscriptions and so-called branded editions ?regional versions of newspapers or those tailored for commuters? in its circulation tally.

Digital subscriptions now account for 19 percent of average U.S. daily newspaper circulation, up from 14 percent last year, the AAM said.

Overall, the average daily circulation at the 593 U.S. newspapers that submitted figures to AAM declined by 0.7 percent from March 2012. The AAM cautioned against comparing the industry's overall numbers with the previous year because of the different ways newspapers have been delivering and selling editions. Some newspapers, for instance, have reduced the number of weekdays that they deliver print editions. Other newspapers are listing branded editions that weren't counted in past years, according to the AAM.

In what was then a break from the industry's practice, The Wall Street Journal began charging for online access to its business-oriented newspaper during the 1990s. That move helped The Journal leapfrog USA Today as the largest U.S. newspaper in 2009.

The New York Times remained the largest Sunday newspaper with an average circulation of 2.32 million, a 16 percent increase from last year. Neither The Journal nor USA Today publishes a print edition on Sunday.

USA Today's weekday circulation fell 8 percent from last year to 1.67 million. The newspaper, owned by Gannett Co., still offers free access to its website. Even so, USA Today delivers a digital version that had nearly 250,000 paying subscribers during the latest period, according to AAM.

After The Journal first emerged with the largest total weekday circulation, USA Today could still claim the largest paid audience in print.

That is no long true though. The Journal's print circulation totaled 1.48 million in the latest period versus 1.42 million at USA Today.

In a statement, USA Today spokeswoman Heidi Zimmerman said the circulation figures don't capture the full scope of the newspaper's audience because the numbers omit digital readers who aren't paying to consume content. For instance, USA Today says it has more than 32 million readers on its website. The newspaper believes it will be able to make more money from that traffic by selling more digital ads.

Source: http://news.yahoo.com/digital-fees-pay-off-2-top-selling-newspapers-222640298.html

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Protests as Luton council cuts free transport to religious schools

Councillors walked out of a meeting at Luton Town Hall this week when observers in the public gallery began shouting and waving placards in protest at the Councils plans to end free transport for pupils attending religious schools.

Members of the executive refused to return until all members of the public had left the building. The council said the cut could save nearly ?300,000 in the first year. In total it needs to cut ?49m from its budget.

Luton currently provides discretionary free transport for children under eight who live between two and 15 miles from their school and between three and 15 miles for over eights. The authority said the cut would save about ?278k in 2013/14 and ?487k in 2014/15.

They are legally obliged to provide the transport for pupils aged 11 to 16 from low income families and this will continue.

About 600 pupils at Cardinal Newman Roman Catholic School will be affected. At present it takes eleven buses a day, including 10 double-deckers, to ferry 600 children to the Cardinal Newman Roman Catholic School inWarden Hill Road.

Parents said it would cost about ?600 per child, per year, to make alternative arrangements. They recently boycotted the transport for one day and drove their children to the school to demonstrate to the council what effect it would have on traffic in the area.

Terry Sanderson, President of the National Secular Society, said: "In all the instances of councils cutting free transport to religious schools, the parents have claimed discrimination. But the real discrimination is against children going to community schools who have to find their own way at their own expense. The parents affected in Luton should be grateful that they've had so much extra money pumped into their children's education over such a long period. They are now going to have to give up this very generous perk ? provided solely on the grounds that they are Catholic ? and pay their way like everyone else has to."

Source: http://www.secularism.org.uk/news/2013/04/protests-as-luton-council-cuts-free-transport-to-religious-schools

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N.Y. Governor Andrew Cuomo signs deal for 2014 book

NEW YORK (Reuters) - New York Governor Andrew Cuomo, considered a possible Democratic contender for the U.S. presidency in 2016, has signed a deal to write a biography that publisher HarperCollins said on Tuesday would be a "full and frank" look at his private and public life.

The publisher said it has acquired world rights to the as-yet untitled book, which it expects to be on the shelves in 2014.

The book will cover his years growing up in Queens, New York, his tenure as Secretary of Housing and Urban Development under President Bill Clinton and his election to the state's top office in 2010.

"He will reveal the story of his history and will share personal and private moments that shaped his life: his father's legacy, his personal trials and tribulations, and his role as a father to his three girls, twins Mariah and Cara and his youngest, Michaela," HarperCollins said in a statement.

Cuomo's father, Mario, also served as governor of New York.

Cuomo, 55, was married to Kerry Kennedy, a daughter of Robert F. Kennedy, for more than a decade until their divorce in 2005. He lives with his girlfriend, Food Network host Sandra Lee, in Westchester County in New York.

The book will also cover his four years as New York's attorney general before becoming the state's 56th governor.

Cuomo will discuss several major events during his governorship, "from signing same-sex marriage legislation to the devastation of Hurricane Sandy and his subsequent work with President Obama to help those who were ravaged by the storm," according to HarperCollins.

(Reporting by Patricia Reaney; editing by Jackie Frank)

Source: http://news.yahoo.com/n-y-governor-andrew-cuomo-signs-deal-2014-141400146.html

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